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Lord of the Risen Reach the Adyr ending.

None Shall be Spared Defeat all bosses.
1/1

Part of the Divine Damarose the Marked receives her divine reward.

Hero Worship Drustan's faith in his brother remains steadfast.

Throwable Collector Collect all throwables.
1/1

Vengeful Reflection An Umbral imprint of Isaac faces the Lightreaper.

Radiant Adept Collect all Radiance spells.
1/1

Travels Resumed Sparky is liberated.

What Sights Contained Within Collect all Umbral Eyes.
1/1

Moving On Byron finds a new purpose.

Ammunition Collector Collect all ammo types.
1/1

Infernal Offerings Donate a total of 10 Severed Hands.
1/1

No Mercy Defeat another player in PVP.

Umbral Adept Collect all Umbral spells.
1/1

I'm The Best There Is... Collect all Trophies

Ultimate Predator Reach Player Level 36
36/36

Repressed Memories Unlock the hidden memory in Nightmare Trials

One More Story Complete the Main Story

A Sinister End Defeat Essex

Small Mercies Set Walter free

Crate Collector Collect all Material Crates
68/68

Pathways of the Mind Discover all Nightmare Doors
14/14

Full Barrel Collect all Whisky Bottles
20/20

A Previous Life Learn the truth about your past

Cut Just As Deep Kill 100 enemies with the Helix Claws
100/100

Had To Put Him Down Defeat Sabretooth

Harmer's Market Destroy all vendor stalls during the Sabretooth boss fight

Undercover Dress up as Patch

Secondary Mutations Reach Adaptation Level 10
10/10

Adamantium Armory Craft enough suits to fully upgrade your Health
20/20

Struck Dead Defeat Deathstrike

Parry Perfected Parry 500 times
500/500

Blindsided Stealth kill 10 enemies blinded by Jean
10/10

Saturn Slam Drop Saturn onto The Hand in Japan

The Monster In Me Survive the Helix Engine

Careful What You Wish For Save "Walter"

That's Cheating Free the stuffed animals from the claw machines

Poseidon's Kiss Activate the kissing toilet in the Tokyo bar bathroom

Spiral Cut Kill 75 enemies with Tornado Spin
75/75

Crash Course Survive Plane Crash

Ground Control Push 3 enemies out of the plane
3/3

A Firm Handshake Meet The Hand

Kicked the Bucket Defeat the Sentinel Prototype

Cache Crusher Destroy 100 XP Caches
100/100

Berserker Unleashed Fly into a Berserker Rage

Hell Raisers Destroy the Refinery

Recycled "Defeat" a Reaver using molten metal

Road Rage Complete Canada Highway Chase

Shish Kebab Impale an enemy on an environmental hazard

Waking Nightmare Discover a Nightmare Door "in the wild"