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Locked 'n Loaded Reach the highest level for any gun with Dante

To Hell With That Kill 100 enemies during the credits

Asylum Defeat Arkham

Left No Stone Unturned Complete all Secret Missions with any Character

Step Into The Light Defeat Doppelganger

Who's Laughing Now? Defeat Jester in all of his forms

That's Not Lady-Like Defeat Lady

Give 'em Hell Max out the Devil Trigger Gauge with Dante

Brotherly Love Fight Vergil a second time and prevail

Rough Rider Defeat Geryon

Lights Out Defeat Beowulf

Lightning In A Bottle Defeat Nevan

Inside Out Defeat the Heart of Leviathan

Sibling Rivalry Survive an encounter with Vergil

Double Trouble Defeat Agni and Rudra

Pest Control Defeat Gigapede

Man's Best Friend Defeat Cerberus

Worst Kept Secret Complete a Secret Mission with any character

Devilish Deed Achieve an S Rank on any mission with any character

Revolt Against the Revolting Destroy a Clockwork Castellan.

Overkill Use a cannon to defeat a zealot.

Grilled Big Cheese Defeat Bitores Méndez.

Shield Your Eyes Defeat 3 enemies at once with a flash grenade.

Talk About Near-Death Experience! Rescue Ashley as she's being carried away by the enemy.

Harpoon Hurler Defeat Del Lago.

I Might Need These Later! Complete the game using 1 or fewer recovery items.

Minimalist Complete the game without opening the item box.

Sensational Work! Complete the game with an S rank.

Sprinter Complete the game in under 2 hours of play time.

Survivor Complete the game on "Standard" or higher.

Veteran Complete the game on "Hardcore" or higher.

Nemesis Down!!! Defeat Stage 3 Nemesis.

Nemesis Down!? Defeat Stage 2 Nemesis.

The Pursuer Follow Nicholai deeper underground.

Kendo's Armory Collect all weapons in the campaign.

RE: Master of Unlocking Unlock all safes, lockers, strongboxes, and pickable locks.

I Need a Hero Withstand the zombie siege.

I Don't Feel So Good Leave the clock tower plaza.

The Carlos Express Leave R.P.D.

An Unfortunate End Defeat zombie Brad.

Escape from the City Make it out of downtown Raccoon City.

Nemesis Down? Defeat Nemesis on the rooftop.

Nemesis Down Cause Nemesis to relinquish an item.

Two For One Deal Defeat two enemies with a single shot.

Power Stones Place all jewels in the clock tower monument.

Get Organized Expand your inventory.

Hello, Charlie! Destroy a Charlie Doll.

Gunsmith Improve a weapon.

Basic Chemistry Craft an item.

Broken Umbrella Witness the true ending.