Seirfan

The Floor Is Lava Get 3 killing blows while wall riding as Lúcio without dying in Quick or Competitive Play.

Simple Geometry Get 3 killing blows with a single use of Hanzo's Storm Arrows in Quick or Competitive Play.

Red Key The other side is calling...

Jacob & Esau You are just like your father...

A Secret Exit Complete ??? 3 times

Power Outage Hack 5 enemies at once as Sombra in Quick or Competitive Play.

Isaac's Heart Kill Isaac with The Lost

Spelunker Boy Beat the Caves/Catacombs without taking damage

Eve's Bird Foot Kill Isaac with Eve

The Razor Kill Satan with Eve

Old Sun Cleared Act 5 (Outer Haven)

Flashback Mania Viewed all flashbacks

Screaming Mantis Doll Defeated Screaming Mantis by non-lethal means, and obtained the Screaming Mantis Doll

Twin Suns Cleared Act 4 (Shadow Moses)

LIQUID! Piloted REX and screamed at your enemy

Lazarus' Rags Kill Isaac with Lazarus

Broken Ankh Kill Satan with Lazarus

Delirious Kill Delirium for the first time

A Blank Card Kill Isaac with Eden

The Book Of Secrets Kill Satan with Eden

The Guillotine Kill Isaac with Judas

New Area Kill Hush for the first time

Judas' Tongue Kill Satan with Judas

The Relic Kill Isaac with Maggy

Lilith Beat Greed Mode with Azazel

The Mind Kill Satan with The Lost

Guardian Angel Kill Satan with Maggy

Blood Rights Kill Satan with Samson

The Negative Beat Sheol 5 times

Mom's Knife Kill Satan with Isaac

Dead Boy Beat the Chest or Dark Room without taking damage

The Chest Beat the Chest

Golden God You are the best!

The Coin Bag Kill Isaac with Cain

Dark Boy Beat the Depths/Necropolis without taking damage

Crying Wolf Doll Defeated Crying Wolf by non-lethal means, and obtained the Crying Wolf Doll

Third Sun Cleared Act 3 (Eastern Europe)

Raging Raven Doll Defeated Raging Raven by non-lethal means, and obtained the Raging Raven Doll

Solid Sun Cleared Act 2 (South America)

The Lost Finish the game's final secret

Daemon's Tail Kill Satan with Azazel

Isaac's Tears Kill Isaac with Isaac

The Polaroid Beat Cathedral 5 times

Hurt me more! Performed an electric shock attack on an enemy soldier using Mk. II/III

Liquid Sun Cleared Act 1 (Middle East)

Drum Can Addict Knocked an enemy soldier flying using a Drum Can

You enjoy all the killing, that's why Killed many enemies in one area, and vomited

Handle with Caution Broke off the most important part of a statue

Hands up! Held an enemy soldier at gunpoint and performed a body check

Survival Expert Use health packs to heal 900 health in a single life in Quick or Competitive Play.