NZBigC

Unforgivable Defeat the Abstract Daddy.

James of All Trades Kill at least one enemy with Wooden Plank, Steel Pipe, Handgun, Shotgun and Rifle in a single playthrough.

Tanning Salon Use the UV Flashlight to kill a Viral.

Your World, Your Rules Complete the game with any ending.

Family First Find your sister.

Going Down Enter the X-13 elevator.

Municipal Services Assign all Facilities.

Boot Licker Reach City Alignment 7 for any faction.

Don Quixote Activate all Windmills.

Brush with Death Wake up after the missile strike.

Debris and Ashes Reach the Observatory.

Known Associate Learn the whereabouts of Veronika Ryan.

Into the Abyss Reach the end of the long staircase.

All Seems in Order Discover the secret of Room 106.

No Big Deal Kill 75 enemies with ranged weapons.
75/75

Find Anything Interesting? Open all Airdrops.

Training Take the training course!

Alone Again Survive the chase in Brookhaven Hospital.

Can't You Read the Signs? Collect all Inhibitors hidden in GRE Quarantines.

Tower Watcher Climb the watchtower

Cat Lover Help Mildred by taking Mortimer to Burt

Higher Ground Reach the hill with the church

Merciless Finish off 50 enemies with a stomp attack.
50/50

Modder Modify your weapons at least 50 times.

Ironheart Max out your Stamina.

Fit as a Fiddle Max out your Health.

Nightmare Fuel Defeat the Flesh Lip.

Ban Hammer Clear all Bandit Camps.

Slowpoke! Lose the maximum level of Chase.

After the Fall Fall from a combined height of at least 10,994 meters.

We Will Be Heard! Restore the radio broadcast tower.

Admitted Reach Brookhaven Hospital.

Leftovers Find the pizza in Pete's Bowl-O-Rama.

Uncanny Meet Maria.

Passed Make your way out of Blue Creek Apartments.

Night Hunter Kill a Volatile.

Get Outta My House! Defeat the Renegades attacking the Fish Eye.

Tickets, Please! Use a Metro Station to Fast Travel.

Tunnel Entrance Activate your first Metro Station.

Light in the Darkness Activate your first Electrical Substation.

Get the Point? Kill 50 enemies with a Spear.

On the Trail of the Enemy Learn Waltz's location.

You're Going Down! Perform 50 takedowns.

Under Pressure Activate your first Water Tower.

That's Teamwork! Kill 100 enemies while playing with at least 2 other players.

Can't Touch This! Kill 20 enemies in a row with melee weapons without taking damage.

Flag Burning Clear your first Bandit Camp.

It Wasn't That Hard, Was It? Defeat your first GRE Anomaly.

Lightning Reflexes Perform a Perfect Block 10 times in a row without taking damage.

Nemesis Meet Skullface