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The House that West Built Unlock all pages of Dr. West's journal.

Absolute Perfection Lauren's waiting, so how about you finish your fights quickly and get 30 Perfects. Sound good?

Platinum Platinum trophy

S Rank Achieve an S Rank and unlock the Crow Wings

Make the Voices Stop Unlocked all other trophies

Dark Boy Beat the Depths/Necropolis without taking damage

Waypoint Fulfilled all pacts for Judgment.

Intensive Care Remove all spears from Trico as quickly as possible.

Mom's Knife Kill Satan with Isaac

Mama's Boy Beat the Womb/Utero without taking damage

Boil, Torch, and Torment Inflict 5 ailments on an archfiend.

Fledgling Collector Find your first treasure.

Lock, Stock, and Barrel Give Trico every single barrel.

Show off Win an online normal survival match without using any magic.

A Queen's Rest Sophesia bestows a final favour.

Abomination Domination Complete Overgrown Temple on Adventure or Apocalypse difficulty.

The Polaroid Beat Cathedral 5 times

Ostiophobia Defeat the son.

Skirmish - Chapter XIII Finish the levels from Chapter XIII in Squire difficulty

Full Master Earn all Gold Medals available in Mastery Challenge

Sweet Melody Capture a creature that creates a beautiful melody.

The Negative Beat Sheol 5 times

Umbral Adept Collect all Umbral spells.
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Solitary Met a strange person in a strange place

Survival Skills Complete Dingy Jungle without using a healing potion or losing a life.

Viva the Violet Complete all Hallelujah Hollow trials

Submerged Mystery Capture a mysterious creature lurking beneath the water's surface.

Isaac's Tears Kill Isaac with Isaac

Radiant Adept Collect all Radiance spells.
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Finally Home Complete every Adventure level in The Journey Home.

Lord of the Risen Reach the Adyr ending.

Chill Out Defeat 5 mobs with a single Ice Wand attack.

Deft Digger Capture a creature that loves to dig holes in the ground.

Magical Milestones Visited many places on pacts.

Pandamonium Complete the Panda Plateau secret mission.

Chemophobia Defeat the trademarked chemical.

Master of Masters Reach master rank 200.

Dressed for the Fest Collect all of the boy's costumes and equip them.

Ammunition Collector Collect all ammo types.
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Vengeful Reflection An Umbral imprint of Isaac faces the Lightreaper.

The Road Traveled Fulfilled all pacts for Remorse.

The Chest Beat the Chest

Lone Champion Complete Lone Fortress on Adventure or Apocalypse difficulty.

Part of the Divine Damarose the Marked receives her divine reward.

What Sights Contained Within Collect all Umbral Eyes.
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Took this thing on a test flight Complete Arcade mode with a custom made ship, at Veteran difficulty level

Ultra, Man! If yer gonna fight, give it your all, pal. Performing 100 Ultra Combos oughta do it, eh?

Syngenesophobia Defeat the brothers.

Stylish Sorcerer Acquired 60 selectable raiments.

Katagelasticism Mock the traitor.