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The Grave Will Out the Truth Uncover the secret in the old house.

Amygdala Defeat Great One: Amygdala.

Chalice of Ailing Loran Acquire the Chalice of Ailing Loran that seals
the tragic land lost to the sands.

Piggyback Ride Carry Cpt. MacMillan to safety.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Mergo's Wet Nurse Defeat Great One: Mergo's Wet Nurse.

All Control Towers disabled Disabled all Control Towers by overriding or destroying them.

Secrets revealed II Solve the second Enigma code

The Choir Gain entry to the realm of the Choir,
the high stratum of the Healing Church.

Street Sweeper In the Main Campaign, killed 50 enemies with the Founder China Broom Shotgun or Vox Heater.

The lives of others Collect all letters

Blood in the Streets Completed Emporia.

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

Secrets revealed III Solve the third Enigma code

Heart of gold Collect all gold items

The Roguish Type In the Main Campaign, used Elizabeth to pick 30 locks.

Sentinel Unlock demolition perk 7

Secrets revealed IV Solve the fourth Enigma code

Higher Learning Completed Comstock House.

Martyr Logarius Defeat Martyr Logarius.

Expert Fortune Hunter Find 80 treasures

Rocket magazine + Unlock demolition perk 5

Get Over Here! Rope pull 5 enemies off edges.

Big Trouble in China Complete Chapter 4 in Leon's campaign.

Celestial Emissary Defeat Great One: Celestial Emissary.

Veteran Complete all chapters on Veteran.

Desperate Measures Corner Zakhaev's Son.

Rescue the Hostages Complete Chapter 1 in Chris' campaign.

ARCADE Hunter Kill 100 enemies in Arcade Multiplayer maps (Arcade only).

Networking Renovate your first Social Club.

On a Clear Day... In the Main Campaign, killed 30 enemies with the Bird's Eye Sniper Rifle.

Hide and Seek Complete Sherry's segment.

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Fashion Victim Purchase all clothing.

Four Fully Upgraded Weapons Fully upgrade four weapons

Auto Enthusiast Purchase all vehicles.

Two For One Deal Defeat two enemies with a single shot.

Agent 894732 Told the truth during the interrogation.

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Fully Improved Weapons Acquired the improved versions of three weapons from Varga.

Stealth Master Made it to the cathedral without being spotted.

Cosplay Kill an Enemy While Playing as an Alternate Character Costume Other Than Drake

Ebrietas, Daughter of the Cosmos Defeat Great One: Ebrietas, Daughter of the Cosmos.

Chalice of Isz Acquire the Great Chalice of Isz that seals
the home of the cosmic kin.

Master Fortune Hunter Find 100 Treasures

Weapon Master Acquire a weapon of the highest level.

Master Thief Collection Find all Treasures and the Strange Relic

The Trouble with Women Complete Chapter 5 in Leon's campaign.

Narcissistic Purchase a new multiplayer character.

Deadeye Shoot 10 enemies off zip lines.