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Night Has Just Begun Complete Breaking News quest.

Strikeout! Eliminate an enemy using a throwable object.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Horn of Plenty Collect all of the Minotaur Horns

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Four Fully Upgraded Weapons Fully upgrade four weapons

It’s getting hot in here... Burn 100 enemies with the Bow of Apollo

Prolific Photographer Take at least one photo in every research group

Dealt with every Little Sister The player has either Harvested or Rescued every possible Little Sister

Souled Out Summon every Soul with the Claws of Hades

Perfectly Restored Collect all the pages in the Sketchbook.

Capture the Moments Complete all the Genie Moments sketches.

The Artist of Denska Known as "the street artist who brought Denska back to life".

Obedience School Deliver 50 kicks to Hounds

Fully Researched Houdini Splicer Fully research the Houdini Splicer

Nice Tan Blind 100 enemies with the Head of Helios

Trusty Steed Reach max bonding level with a horse.

Big Game Hunter In the Main Campaign, killed 100 enemies with the Founder Huntsman Carbine or Vox Burstgun.

Loose Cannon In the Main Campaign, killed 25 enemies with the Paddywhacker Hand Cannon.

Fully Researched Rosie Fully research the Rosie

Feelin' A Little Stabby Kill an enemy, knifing them with a gun blade.

Fully Researched Nitro Splicer Fully research the Nitro Splicer

Uphold the Law Issue a ticket.

Lucky Winner Hit the jackpot at a slot machine

Fully Researched Little Sister Fully research the Little Sister

Familiar Methodologies Fight off Hartman

Irony The player has taken a picture of Sander Cohen's corpse

Nukem! Eliminate 3 enemies with 1 explosive.

Five Fully Upgraded Weapons Fully upgrade five weapons

Back in the Saddle Help train the local militia.

Dead or Alive Complete Soot's Final Encore quest.

Hit Man Perform a 1000-hit combo

Fully Researched Bouncer Fully research the Bouncer

Priceless Collect all of the ‘Godly Possessions’

I'd Buy That For a Dollar! Find an OCP skill disk.

All Adds Up Equip Auto-9's PCB with any chip.

Raising the Bar In the Main Campaign, upgraded one attribute (Health, Shield, or Salts) to its maximum level.

Aerial Assassin In the Main Campaign, killed 20 enemies with a Sky-Line Strike.

aMAZEd Beat the Labyrinth without dying or failing

Danger Close Get hand picked for Shepherd's elite squad.

Officer of the month Score "A" on any evaluation.

Live by the bike... Shoot the gas tank of a moving motorcycle.

Hard Boiled Help officers Kurtz and O'Neal solve a murder case.

Dead-On Score 150 points at the shooting range.

Lock and Load Customize a multiplayer loadout

Two Birds with One Stone Kill 2 enemies with a single bullet.

No stone unturned Find a secret area in the Arcade.

Three-some Kill at least 3 enemies with a single shot from a grenade launcher.