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Run-and-Gunner Kill 20 Enemies by Shooting from the Hip (without aiming)

Vaporize Unlock demolition perk 6

LKW battery + Unlock assault perk 7

These Walls Can't Stop Me Beat 'Chapter 5 - The Fortress' in less than 10 minutes

50 Kills: M32-Hammer Kill 50 Enemies with the M32-Hammer

Grenade Hangman Kill 10 Enemies with Grenades While Hanging

Fully Researched Gun Splicer The player has fully researched the Leadhead Splicer

Charted! - Normal Finish the Game on Normal Without Changing the Difficulty

Survival Instincts Defeat the Empress Jaguar

250 Headshots Defeat 250 Enemies with Headshots

30 Kills: RPG-7 Kill 30 Enemies with the RPG-7

Look, Over There! Kill 3 enemies while they are distracted

Secrets revealed I Solve the first Enigma code

Relic Finder Find the Strange Relic

A Speedy Reunion Beat 'Chapter 16 - The Treasure Vault' in less than 7 minutes

Explosive Surprise Kill 5 enemies with sabotaged vehicles (Campaign only).

You Know the Germans Make Good Stuff... Collect all Uber Chests

Proficient Fortune Hunter Find 60 Treasures

Charted! - Crushing Finish the Game on Crushing Without Changing the Difficulty

Ammo Inventor The player has successfully invented all possible ammo types

30 Kills: SAS-12 Kill 30 Enemies with the SAS-12

ARCADE Enthusiast Successfully complete 10 featured Arcade maps in Solo or Co-op (Arcade only).

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Bullseye Unlock demolition perk 4

Death From Above Drop a bomb from a plane and destroy or disable 4 vehicles at once (Campaign only).

30 Kills: T-Bolt Sniper Kill 30 Enemies with the T-Bolt Sniper

Ace Killer Destroy 10 planes while driving any aerial vehicle (Campaign only).

Adept Fortune Hunter Find 60 Treasures

Secrets revealed II Solve the second Enigma code

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

Expert Fortune Hunter Find 80 treasures

The lives of others Collect all letters

Steel Fist Master Kill 20 Enemies with a Single Punch After Weakening Them with Gunfire

Secrets revealed III Solve the third Enigma code

Heart of gold Collect all gold items

Sentinel Unlock demolition perk 7

Been There, Done That Complete all Hunting & Fishing Challenges (Campaign only).

Secrets revealed IV Solve the fourth Enigma code

Rocket magazine + Unlock demolition perk 5

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Four Fully Upgraded Weapons Fully upgrade four weapons

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Fire of Life Enter the Temple of Life's inner chamber

Master Fortune Hunter Find 100 Treasures

Cosplay Kill an Enemy While Playing as an Alternate Character Costume Other Than Drake

ARCADE Hunter Kill 100 enemies in Arcade Multiplayer maps (Arcade only).

Master Thief Collection Find all Treasures and the Strange Relic

Treasures from the Past Decipher a Monolith

Asking Price Buy an item from a merchant

It’s getting hot in here... Burn 100 enemies with the Bow of Apollo