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Fully Researched Gun Splicer The player has fully researched the Leadhead Splicer

Explosion Man Kill 20 enemies with explosives in a single level.

Survival Instincts Defeat the Empress Jaguar

250 Headshots Defeat 250 Enemies with Headshots

30 Kills: RPG-7 Kill 30 Enemies with the RPG-7

Look, Over There! Kill 3 enemies while they are distracted

Maxed Out! Completely upgrade all weapons

Everything Lost Again Complete Act 01

Proficient Fortune Hunter Find 60 Treasures

Charted! - Crushing Finish the Game on Crushing Without Changing the Difficulty

Hardware Fail Shoot out a tire on 15 different vehicles

Ammo Inventor The player has successfully invented all possible ammo types

Two Souls Launched a scene in Duo mode.

Teammates Did 3 mischievous things with Jodie and Aiden.

Sorry Forgave Jodie's father.

A Waist of Space Expand inventory slots to max.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

All Control Towers disabled Disabled all Control Towers by overriding or destroying them.

Piggyback Ride Carry Cpt. MacMillan to safety.

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

Expert Fortune Hunter Find 80 treasures

Steel Fist Master Kill 20 Enemies with a Single Punch After Weakening Them with Gunfire

Agent 894732 Told the truth during the interrogation.

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Four Fully Upgraded Weapons Fully upgrade four weapons

Fire of Life Enter the Temple of Life's inner chamber

Master Fortune Hunter Find 100 Treasures

Fully Improved Weapons Acquired the improved versions of three weapons from Varga.

Barreled Right Over Them Kill an enemy with an exploding barrel.

Cosplay Kill an Enemy While Playing as an Alternate Character Costume Other Than Drake

Master Thief Collection Find all Treasures and the Strange Relic

Stealth Master Made it to the cathedral without being spotted.

Treasures from the Past Decipher a Monolith

Desperate Measures Corner Zakhaev's Son.

Hide and Seek Complete Sherry's segment.

Asking Price Buy an item from a merchant

Channeling Master Channeled all dead bodies in the condenser compound.

It’s getting hot in here... Burn 100 enemies with the Bow of Apollo

Cold Blood Did not impress or scare the teens with Aiden.

Platinum Earn all Uncharted: Drake's Fortune™ Remastered Trophies

Dyno-Might Master Kill 5 Enemies with 1 Explosion

Eye for an Eye Didn't speak during the interrogation.

The Hidden City Find Paititi

All Animal Figurines found Found all of the Animal Figurines in the Cut.

All Pigments found Found all of the Pigments in the Cut.

Killed 6 Fireclaws Killed 6 Fireclaw machines.

Win the War Complete the game on any difficulty.

First Blood Perform a Stealth Takedown from a mud-covered wall

Prolific Photographer Take at least one photo in every research group