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Down with the Sickness Reach the highest tier of Autophage infection by equipping Autophage Skills.

Eviscerator Kill 30 enemies with the Line Gun

Ghosts and Stuff Complete all secondary content.

Gwent Master Defeat Tybalt and win the gwent tournament held at the Passiflora.

Hat Trick Destroy 3 enemy Titans with 1 Core ability in the Campaign

Brag Rags Earn 1 star in Special Ops Mission Mode.

Master Of All You Survey Discover all named locations.
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Slaughterhouse 3 Complete all the Circles of Slaughter.
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Judo Master Throw 50 enemies with Grapple

David & Goliath Take down the LCS on the first go.

Redemption Complete 'Red Dead Redemption'.

Spreading the Word Clear all threat in Pink Eye's territory

Cowboy Up Rodeo an enemy Titan in the Campaign

Bomb Specialist Clear all minefields

Married Get married

Leave It to the Pro Complete the entire game on Professional.

Clockwerk Collector Collect over 20 treasures.

Mercenary Complete 50 Misc. Objectives

Sparrow Approves Use the compass many times to navigate.

...A Saint Gets a Gun Ring all the bells in town in 'Miracle on 3rd Street'.

The Constructionist Build all projects in all strongholds

Urban Explorer Discover all named locations in Sanctuary, Opportunity, and Lynchwood.

That Is the Evilest Thing… Ignite the gas produced by a Dragon's Dream bomb using a burning opponent. Do this 10 times.

High-Flying Hurler Kill a flying enemy with a thrown Tediore weapon.

Standing Stones Find 13 Standing Stones

…They're Action Figures Collect 20 Vault-Tec Bobbleheads

Reach Anor Londo Arrive in Anor Londo.

The Temples Complete all levels in The Temples

Go, Bobcats! Reunite all the VCLA Bobcats.

Icing the Cake In Snow Day, score a goal from your own side of the ice

Savings Account Unlock the Cooper Safe in Episode 3.

Speak Friend and Enter Open one of the Ithildin Doors.

Cult Master Defeat the cultists.

Mad Skillz Max out all the skills that allow you to level up.

Arcade Operator Repair any arcade machine.

Getting A Little On The Side Complete all Side Missions.
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Maximum Air Be airborne in a vehicle for 4 seconds or more and land without dying

Eavesdropper In the Main Campaign, collected every Voxophone.

Cowboy Builder Complete 'A New Jerusalem'.

Can't touch this Use a hammer to kill a series of 15 zombies without taking damage.

Minty Fresh! Lick the candy cane barricade all the way through in 'The Fight Before Christmas'.

Sideways Complete 10 side quests

En Guardian! Awarded for defeating the Guardian of the Woods and bringing him back to his senses.

Sightseer In the Main Campaign, used all telescopes and Kinetoscopes in the game.

Zenny, Gil, or Just Loot Unlock the Cooper Safe in Episode 4.

Lordvessel Acquire the Lordvessel.

Endless Summer Complete the Epilogue.

Art of Abysswalking Acquire the Art of Abysswalking.

Check Please Unlock the Cooper Safe in Episode 5.

A Cut Above Kill 30 enemies with the Ripper