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Perfect Clear: Labyrinth Beat the boss " Labyrinth" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Aggressor Beat the boss "Aggressor" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Centrifuge Beat the boss "Centrifuge" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Vestige Beat the boss "Vestige" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Fusillade Beat the boss "Fusillade" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Aberration Beat the boss "Aberration" with a perfect clear, also not using missiles or consumables.

Perfect Clear: The Warden Beat the boss "The Warden" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Terminus Beat the boss "Terminus" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Periphery Beat the boss "Periphery" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Metal Legion Beat the boss "Metal Legion" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Sunder Beat the boss "Sunder" with a perfect clear, also not using missiles or consumables.

Perfect Clear: The Humbled Beat the boss "The Humbled" with a perfect clear, also not using missiles or consumables.

Perfect Clear: Valor Beat the boss "Valor" with a perfect clear, also not using missiles or consumables.

Perfect Clear: All Bosses Beat each base game boss with a perfect clear, also not using missiles or consumables.

Perfect Clear: All Mini Bosses Beat each miniboss with a perfect clear, also not using missiles or consumables.

Kill Final Boss With Deep Blue Mech Kill the "final" boss while using the Deep Blue mech.

Kill Final Boss With Redshift Mech Kill the "final" boss while using the Redshift mech.

Kill Final Boss With Humble Mech Kill the "final" boss while using the Humble mech.

Kill Final Boss With Alpha Mech Kill the "final" boss while using the Alpha mech.

Kill Final Boss With Penumbra Mech Kill the "final" boss while using the Penumbra mech.

Kill Final Boss With All Mechs Kill the "final" boss with each of the original six mechs.

Kill Super-Final Boss With Deep Blue Mech Kill the "real" final boss with the Deep Blue mech.

Kill Super-Final Boss With Green Envy Mech Kill the "real" final boss with the Green Envy mech.

Kill Super-Final Boss With Flame Tank Mech Kill the "real" final boss with the Flame Tank mech.

Kill Super-Final Boss With Indigo Dipole Mech Kill the "real" final boss with the Indigo Dipole mech.

Kill Super-Final Boss With Redshift Mech Kill the "real" final boss with the Redshift mech.

Kill Super-Final Boss With White Gloss Mech Kill the "real" final boss with the White Gloss mech.

Kill Super-Final Boss With Humble Mech Kill the "real" final boss with the Humble mech.

Kill Super-Final Boss With Alpha Mech Kill the "real" final boss with the Alpha mech.

Kill Super-Final Boss With Penumbra Mech Kill the "real" final boss with the Penumbra mech.

Kill Super-Final Boss With All Mechs Kill the "real" final boss with each of the original six mechs.

Complete Run With Incredibility: Life Harvester Pick up the Incredibility Life Harvester on the first floor, never drop it, and win the run.

Complete Run With Incredibility: Consummate Consumer Pick up the Incredibility Consummate Consumer on the first floor, never drop it, and win the run.

Complete Run With Incredibility: Minimalist Pick up the Incredibility Minimalist on the first floor, never drop it, and win the run.

Complete Run With Incredibility: The One Pick up the Incredibility The One on the first floor, never drop it, and win the run.

Complete Run With Incredibility: Magnetic Personality Pick up the Incredibility Magnetic Personality on the first floor, never drop it, and win the run.

Complete Run With Incredibility: Jaywalker Pick up the Incredibility Jaywalker on the first floor, never drop it, and win the run.

Complete Run With Incredibility: Confidence Pick up the Incredibility Confidence on the first floor, never drop it, and win the run.

Complete Run With Incredibility: The Creator Pick up the Incredibility The Creator on the first floor, never drop it, and win the run.

Complete Run With Incredibility: Lilliputians Pick up the Incredibility Lilliputians on the first floor, never drop it, and win the run.

Complete Run With Incredibility: High Speed Danger Pick up the Incredibility High Speed Danger on the first floor, never drop it, and win the run.

An Entourage Befitting A Hydral Have 5 familiars at once.

Safari Kill at least one of each non-boss enemy.

Untouchable Complete a floor with no damage.

Conspicuous Nonconsumption Complete a run without buying any items.

Noncommittal Complete a run without picking up any attachment items.

Dominate Berserker Complete all Challenges related to Berserker.

Dominate Commander Complete all Challenges related to Commander.

Compliment Located Let the Apostle poke fun at Wenny.

The More the Merrier Have 30 or more cards in your deck when you complete a game.