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Micolash, Host of the Nightmare Defeat Micolash, Host of the Nightmare.

Civic Leader Take over all territory in the Warren.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Amygdala Defeat Great One: Amygdala.

Chalice of Ailing Loran Acquire the Chalice of Ailing Loran that seals
the tragic land lost to the sands.

Desperate Measures Corner Zakhaev's Son.

It’s getting hot in here... Burn 100 enemies with the Bow of Apollo

The Guardian Orb The Guardian Orb

When Freedom Calls Complete "When Freedom Calls"

Mergo's Wet Nurse Defeat Great One: Mergo's Wet Nurse.

Urban Designer Take over all territory in the Historic District.

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

The Choir Gain entry to the realm of the Choir,
the high stratum of the Healing Church.

Merman's Delite Acquire the Triton Lance

Win the War Complete the game on any difficulty.

Back at Ya! Finish parry puzzle

Martyr Logarius Defeat Martyr Logarius.

Horsing Around Awaken all three horses

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Celestial Emissary Defeat Great One: Celestial Emissary.

You're so Sly Collect all Dead Drops in the Historic District.

Four Fully Upgraded Weapons Fully upgrade four weapons

A Keen Sense of Spell Invoke Ancient Magic for the first time

Souled Out Summon every Soul with the Claws of Hades

Chain Gang Break the Chains of Tartarus

Welcome Park Prize Play through all the tutorials in Welcome Park.

E1M1 Complete the first mission of the campaign

Chalice of Isz Acquire the Great Chalice of Isz that seals
the home of the cosmic kin.

Ebrietas, Daughter of the Cosmos Defeat Great One: Ebrietas, Daughter of the Cosmos.

Weapon Master Acquire a weapon of the highest level.

The Power Glove Acquire Gauntlet of Zeus

Bow Down Move the Titan, Hyperion

Almost There… Running across the long chain

Fare Thee Well Kill Charon, the Ferryman

Obedience School Deliver 50 kicks to Hounds

Tree Hugger Sacrifice powers

Dead Beat Dad Push away Calliope

Eye for an Eye Collect all the Gorgon Eyes

Nice Tan Blind 100 enemies with the Head of Helios

Born Survivor Reach Level 5

Evil Train Bad guys make it clear who the boss is.

Atlas in Chains Chain the Titan, Atlas

Hades Needs a New Wife Kill Persephone

You Complete Me Completely upgrade all weapons and magic

For the Birds Collect all the Phoenix Feathers

It's Over Already? Beat the game

The Package Complete 'Crew Expendable' on Veteran difficulty.

Prolific Photographer Take at least one photo in every research group

Hotfoot Travel 25 kilometers while riding the rails.