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Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Four Fully Upgraded Weapons Fully upgrade four weapons

An Unfortunate End Defeat zombie Brad.

I Don't Feel So Good Leave the clock tower plaza.

I Need a Hero Withstand the zombie siege.

Two For One Deal Defeat two enemies with a single shot.

The Pursuer Follow Nicholai deeper underground.

Nemesis Down Cause Nemesis to relinquish an item.

Nemesis Down!? Defeat Stage 2 Nemesis.

Nemesis Down!!! Defeat Stage 3 Nemesis.

The War at Home Complete the World War I simulation.

You Better Start Running Escape from the Baker family home.

Prolific Photographer Take at least one photo in every research group

Dealt with every Little Sister The player has either Harvested or Rescued every possible Little Sister

Treasure Hunter Complete ten Raids of any type with Jacob or Evie.

A Broad Base Reach Loyalty level 1 with all Associates.

Playing it Safe Complete the game on Easy.

Into the Depths Escape from the ship.

A Quarter-Furlong at a Time Finish first in 3 different Street Races.

Opium Scourge Affect at least four enemies simultaneously with the Hallucinogenic Dart.

Fully Researched Houdini Splicer Fully research the Houdini Splicer

Like A Bat Outta Hell Defeat Tiamat

A Threat Rises Completed Chapter 1 of Episode 2

Whirlwind of Death Perform fifty Multi-Finishers.

Strange Bedfellows Completed Chapter 2 of Episode 2

Unsure Footing Completed Chapter 3 of Episode 2

A Family Affair Completed Chapter 4 of Episode 2

Don't Make Me Angry Collect the Chaos Form Ability

Behind Enemy Lines Completed Chapter 5 of Episode 2

Whirlwind Completed Chapter 6 of Episode 2

Slayer Kill 666 Demons
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Fully Researched Rosie Fully research the Rosie

Unexpected Encounter Completed Chapter 1 of Episode 3

Power Stones Place all jewels in the clock tower monument.

Be Kind, Please Rewind Watch all the videotapes in a single playthrough.

Shot in the Dark Completed Chapter 2 of Episode 3

Motley Crew Completed Chapter 3 of Episode 3

In the Line of Duty Completed Chapter 5 of Episode 3

Hive of Villainy Completed Chapter 4 of Episode 3

Descent Into Darkness Completed Chapter 6 of Episode 3

A Shadow Falls Completed Chapter 3 of Episode 5

Defender Completed Chapter 2 of Episode 5

Funny or Die Completed Chapter 1 of Episode 5

What Had To Be Done Completed Chapter 4 of Episode 4

Breach of Darkness Completed Chapter 1 of Episode 4

Darkest Night Completed Chapter 2 of Episode 4

Fractured Completed Chapter 4 of Episode 5

The Punchline Completed Chapter 6 of Episode 4

Fortune Reversed Completed Chapter 3 of Episode 4