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Explosion Man Kill 20 enemies with explosives in a single level.

Welcome to the Crimson Raiders Complete mission "Children of the Vault".

In the Bag Increase your item slots.

No Rest for the Weary Stab an injured crawling enemy.

Tear 'em a New One In the Main Campaign, opened 30 Tears.

Armed Revolt Assisted the gunsmith.

Fist of the South Star Defeat an opponent in a fistfight without taking any damage.

Death Mode: Rowdy Cloudy Complete the Death Mode level.

Vigorous Opposition In the Main Campaign, killed 75 enemies either with a Vigor or while the enemy is under the effects of a Vigor.

Fully Researched Gun Splicer The player has fully researched the Leadhead Splicer

Death Mode: Purgatory #2 Complete the Death Mode level.

Should Auld Acquaintance... Unlocked 1999 Mode.

Let's Cook! Learn 12 potion formulae.

Working Class Hero In the Main Campaign, completed the Factory.

Silent Killer Use a stealth attack to take down five enemies.

First Errand Complete your first quest.

Maxed Out! Completely upgrade all weapons

Hardware Fail Shoot out a tire on 15 different vehicles

A Meeting with Destiny Completed Episode 5.

Reinforcement Denied Kill at least 3 rappelling enemies in a single rope.

Micolash, Host of the Nightmare Defeat Micolash, Host of the Nightmare.

Cainhurst Gain entry to Cainhurst, the lost and ruined castle.

Ammo Inventor The player has successfully invented all possible ammo types

Lifesaver Help or rescue your partner ten times.

Eye Candy Collect all of the Gorgon Eyes

Get on the Plane Complete Chapter 3 in Leon's campaign.

Amygdala Defeat Great One: Amygdala.

Chalice of Ailing Loran Acquire the Chalice of Ailing Loran that seals
the tragic land lost to the sands.

Zombie Massacre Defeat 500 zombies.

Piggyback Ride Carry Cpt. MacMillan to safety.

The Grave Will Out the Truth Uncover the secret in the old house.

Mergo's Wet Nurse Defeat Great One: Mergo's Wet Nurse.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Horn of Plenty Collect all of the Minotaur Horns

The Choir Gain entry to the realm of the Choir,
the high stratum of the Healing Church.

Street Sweeper In the Main Campaign, killed 50 enemies with the Founder China Broom Shotgun or Vox Heater.

Fearless Defeat a Deathless Swordsman using only melee attacks and a finisher

Blood in the Streets Completed Emporia.

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

Get Over Here! Rope pull 5 enemies off edges.

It's a Healthy Baby Boy! Complete the desert area.

The Roguish Type In the Main Campaign, used Elizabeth to pick 30 locks.

Martyr Logarius Defeat Martyr Logarius.

Veteran Complete all chapters on Veteran.

Higher Learning Completed Comstock House.

Celestial Emissary Defeat Great One: Celestial Emissary.

Big Trouble in China Complete Chapter 4 in Leon's campaign.

Desperate Measures Corner Zakhaev's Son.

The Lost City Completed Episode 6.

Rescue the Hostages Complete Chapter 1 in Chris' campaign.