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Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Four Fully Upgraded Weapons Fully upgrade four weapons

Eye Sore Collect 20 Cyclops Eyes

Little Sister Savior The player has completed the game without harvesting any Little Sisters

"YOU'RE NOT EVEN LISTENING TO ME!!!" Ask Lupe about her organizational system.

Fully Improved Weapons Acquired the improved versions of three weapons from Varga.

"Plus, we look good in these clothes!" Talk to Glottis about leaving.

Head Hunter Use the Precision ability to rack up three head shots in rapid succession.

Lord of the Seas Upgrade the Adrestia to Legendary Status.

Bookworm Read 30 books, journals or other documents.

Cosplay Kill an Enemy While Playing as an Alternate Character Costume Other Than Drake

Master Fortune Hunter Find 100 Treasures

Fried Friendship It takes two to… torture.

"We are all citizens of the same nation, and our king rides a pale horse." Try to get a passport from Chowchilla Charlie.

Master Thief Collection Find all Treasures and the Strange Relic

It’s getting hot in here... Burn 100 enemies with the Bow of Apollo

"Well, maybe just a sip..." Sample the Marillo de Oro.

Narcissistic Purchase a new multiplayer character.

Deadeye Shoot 10 enemies off zip lines.

The Trouble with Women Complete Chapter 5 in Leon's campaign.

Struck A Pose Self-inflicted paparazzi.

Trust Me, I'm a Doctor Complete the Hippokrates questline.

Tin Soldier Completed the Main Campaign on Easy difficulty or above.

"We're straight stingers, you know?" Talk to the worker bees about playing the game.

Platinum Earn all Uncharted: Drake's Fortune™ Remastered Trophies

A Pirate's Life for Me Complete Xenia's questline.

The Bird or The Cage Completed The Hand of the Prophet.

Bigger Bang Complete story mode on Normal difficulty

All Animal Figurines found Found all of the Animal Figurines in the Cut.

"Great news -- we've discovered a new, secret talent of our tiny messengers!" Catch up on how the pigeons are doing.

He's Gonna Need a Sturgeon Hit 3 Enemies with Fish in the Market

Stockpile Obtain all available weapons.

Dyno-Might Master Kill 5 Enemies with 1 Explosion

Vehicular Manslaughter Defeat 25 enemies by throwing cars at them.

All Pigments found Found all of the Pigments in the Cut.

Death Mode: Spiral Staircase Complete the Death Mode level.

Prolific Photographer Take at least one photo in every research group

"Consider it an homage." Have Olivia recite one of your poems.

Killed 6 Fireclaws Killed 6 Fireclaw machines.

On My Way Up Reach level 10 in multiplayer.

Dealt with every Little Sister The player has either Harvested or Rescued every possible Little Sister

"Manny, we've given up. All of us." Talk to Membrillo about why he's still here.

Master of Pyrotechnics In the Main Campaign, killed 20 enemies with the Barnstormer RPG.

Hermes's Homie Unveil all sub-regions of Greece.

"It shone, pale as bone..." Look at the moon.

"So, sorry, but I don't do... 'odd jobs.'" Try to convince Verago to help you out.

They Belong in a Museum Obtain all treasures in the game.

Evil Train Bad guys make it clear who the boss is.

Child of Poseidon Complete all underwater location objectives.

Cheat Hard to Cheat Harder Activate a Tweak