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The One Reborn Defeat the One Reborn.

Vigorous Opposition In the Main Campaign, killed 75 enemies either with a Vigor or while the enemy is under the effects of a Vigor.

Fully Researched Gun Splicer The player has fully researched the Leadhead Splicer

Charted! - Normal Finish the Game on Normal Without Changing the Difficulty

No Rest for the Weary Stab an injured crawling enemy.

Should Auld Acquaintance... Unlocked 1999 Mode.

Help A Brother Out Complete a Templar Hunt sequence.

Working Class Hero In the Main Campaign, completed the Factory.

Relic Finder Find the Strange Relic

Just Like Starting Over Complete memory sequence 12.

It's All Good Complete present day mission 5.

Thug Life Plunder 30 ships.

Saw That One Coming... Complete memory sequence 13.

Teammates Did 3 mischievous things with Jodie and Aiden.

Two Souls Launched a scene in Duo mode.

Ammo Inventor The player has successfully invented all possible ammo types

30 Kills: SAS-12 Kill 30 Enemies with the SAS-12

Cainhurst Gain entry to Cainhurst, the lost and ruined castle.

Micolash, Host of the Nightmare Defeat Micolash, Host of the Nightmare.

Sorry Forgave Jodie's father.

All Control Towers disabled Disabled all Control Towers by overriding or destroying them.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Reinforcement Denied Kill at least 3 rappelling enemies in a single rope.

Amygdala Defeat Great One: Amygdala.

Chalice of Ailing Loran Acquire the Chalice of Ailing Loran that seals
the tragic land lost to the sands.

Killer Killer Harpoon a killer whale.

Mergo's Wet Nurse Defeat Great One: Mergo's Wet Nurse.

30 Kills: T-Bolt Sniper Kill 30 Enemies with the T-Bolt Sniper

Piggyback Ride Carry Cpt. MacMillan to safety.

The Choir Gain entry to the realm of the Choir,
the high stratum of the Healing Church.

Blood in the Streets Completed Emporia.

Street Sweeper In the Main Campaign, killed 50 enemies with the Founder China Broom Shotgun or Vox Heater.

Adept Fortune Hunter Find 60 Treasures

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

The Roguish Type In the Main Campaign, used Elizabeth to pick 30 locks.

Higher Learning Completed Comstock House.

Martyr Logarius Defeat Martyr Logarius.

Celestial Emissary Defeat Great One: Celestial Emissary.

Agent 894732 Told the truth during the interrogation.

On a Clear Day... In the Main Campaign, killed 30 enemies with the Bird's Eye Sniper Rifle.

Fully Improved Weapons Acquired the improved versions of three weapons from Varga.

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Four Fully Upgraded Weapons Fully upgrade four weapons

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Desperate Measures Corner Zakhaev's Son.

Stealth Master Made it to the cathedral without being spotted.

Ebrietas, Daughter of the Cosmos Defeat Great One: Ebrietas, Daughter of the Cosmos.

Chalice of Isz Acquire the Great Chalice of Isz that seals
the home of the cosmic kin.

Channeling Master Channeled all dead bodies in the condenser compound.

Weapon Master Acquire a weapon of the highest level.