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Death From Above Drop a bomb from a plane and destroy or disable 4 vehicles at once (Campaign only).

Mergo's Wet Nurse Defeat Great One: Mergo's Wet Nurse.

Zombie Massacre Defeat 500 zombies.

Ace Killer Destroy 10 planes while driving any aerial vehicle (Campaign only).

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Piggyback Ride Carry Cpt. MacMillan to safety.

The Choir Gain entry to the realm of the Choir,
the high stratum of the Healing Church.

Wonder of the Age Reach Level 10.

"...Used to scream like a banshee when the trade winds blew..." Ask Velasco about his eye patch.

"We only have one mop." Check your job qualifications with Celso.

WHAT IS WRONG WITH YOU Flip five vehicles by shooting their horses.

Year 1 Spend a year in the Eighth Underworld.

Out for Justice Learn what it means to be a Scaletta.

Blood in the Streets Completed Emporia.

Get Over Here! Rope pull 5 enemies off edges.

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

Adept Fortune Hunter Find 60 Treasures

Doctor Cole Heal 250 pedestrians.

Martyr Logarius Defeat Martyr Logarius.

Celestial Emissary Defeat Great One: Celestial Emissary.

Expert Fortune Hunter Find 80 treasures

Been There, Done That Complete all Hunting & Fishing Challenges (Campaign only).

The Dip You set a new record.

Entrapment Catch a player in a snare trap in multiplayer.

Next time use the stairs Complete the Gauntlet of Archimedes

Big Trouble in China Complete Chapter 4 in Leon's campaign.

"YOU'RE NOT EVEN LISTENING TO ME!!!" Ask Lupe about her organizational system.

Home Run You are clearly good with a bat.

Steel Fist Master Kill 20 Enemies with a Single Punch After Weakening Them with Gunfire

Rescue the Hostages Complete Chapter 1 in Chris' campaign.

"Plus, we look good in these clothes!" Talk to Glottis about leaving.

Chimney Sweep Synchronize every Viewpoint in London.

Bond Broken Complete the Game

Men at Work Complete Chapter 14.

Agent 894732 Told the truth during the interrogation.

The Beast Beater Destroy Metal Head Beasts

Desperate Measures Corner Zakhaev's Son.

Sharp Suiter Buy your first luxury suit.

"We are all citizens of the same nation, and our king rides a pale horse." Try to get a passport from Chowchilla Charlie.

Proper Scrapper Sell five vehicles to Mike Bruski at the scrapyard.

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Chalice of Isz Acquire the Great Chalice of Isz that seals
the home of the cosmic kin.

Ebrietas, Daughter of the Cosmos Defeat Great One: Ebrietas, Daughter of the Cosmos.

Street Sweeping Conquer all the boroughs in London

Four Fully Upgraded Weapons Fully upgrade four weapons

Stealth Master Made it to the cathedral without being spotted.

Finish Him Finish What you started.

"Well, maybe just a sip..." Sample the Marillo de Oro.

Master Fortune Hunter Find 100 Treasures