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The Negative Beat Sheol 5 times

Quadruplets! Pigsy's Perfect 10: Ally 4 enemies using one single Ally device.

Centennial Acquire 100% of the Stars

Not a Scratch Finish with your tank at full health in the "Iron Clad" Special Ops mission.

Siege Complete the "Light 'Em Up" Special Ops mission on any difficulty.

Block Party Beat Ken Block in a Throwdown.

Hypersonic Complete all Secret Encounters in a single save slot (Ancient Gods 1)

GD Parkour Instructor Complete all Parkour Fever Challenges at night

Mine Sweeper Destroy 10 turrets or traps using Winston's Tesla Cannon without dying in Quick or Competitive Play.

Peerless Marksman Unlocked every panel in the marksman job tree.

Umbral Adept Collect all Umbral spells.
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Take a Chance Unlocked the gambler.

Skilled Adversary In IX have a Challenge banner with all 9 medallions

Isaac's Tears Kill Isaac with Isaac

Path of the Summoner Unlocked the summoner.

Rest Your Weary Fists Kill the Dark Lord (Ancient Gods 2)

I never doubted you! Win 10 Rounds of Infiltration

Swimming with the Fishes In Voyage of Despair, kill 50 zombies that are underwater in a single game

Egg-stra XP! Complete the Egg-Stra XP challenge and then destroy a hive in the Onslaught DLC package.

Pretentious Do not use any item during a mission

Radiant Adept Collect all Radiance spells.
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Downforce Completionist Gain all stars in 'Downforce'.

Genpei Demon Completed all missions in "The Tengu's Disciple" on Dream of the Demon. (Does not include Twilight or training missions.)
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Lord of the Risen Reach the Adyr ending.

Untouchable Use only one self revive care package in the "Special Delivery" Special Ops mission.

Mirra Image Beat Dave Mirra in a Throwdown.

Lamborghini Completionist Gain all stars in 'Lamborghini'.

Midnight Completionist Gain all stars in 'Midnight'.

Yeeee HAW! Complete the Adventure Mode on the Hard difficulty.

dr0n3d Complete the "Arctic Recon" Special Ops mission in under 3:30.

Critical Literature Collect all physical Codex pages in a single save slot (Ancient Gods 2)

Things That Go Ka-Boom Learn how to craft Exploding Arrows

High Roller Complete the "Iron Clad" Special Ops mission on Veteran difficulty.

Vengeful Reflection An Umbral imprint of Isaac faces the Lightreaper.

The Chest Beat the Chest

Ammunition Collector Collect all ammo types.
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Electric Whisper Learn how to craft Electric Arrows

Pea Shooter Kill a Rhino with only a pistol in Nightfall in Regular or Hardcore difficulty.

Monster Farmer Kill at least 300 of the same type of monster.

Gun Nut Equip 15 Weapon Attachments.

Horsepower Completionist Gain all stars in 'Horsepower'.

Part of the Divine Damarose the Marked receives her divine reward.

Backwards & Forwards Complete ALL levels in N. Verted mode

Elements Completionist Gain all stars in 'Elements'.

Don't Talk to Rangers Kill 150 Tormentors and Spikers.

What Sights Contained Within Collect all Umbral Eyes.
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Seal the Deal Complete a Triumph Seal.

A shining inspiration to us all! Achieve the rank of Grand Lord (Rank 25).

Conflagration Finish Mission 6

Perfect 10 Pigsy's Perfect 10: Finish the Shooting Gallery under 40 seconds without shooting any pin-ups.