Whoacoder

Closure Experienced the end of the cycle.(Not available in Casual Mode)

Bloody Lust Kill Isaac with Samson

A Blank Card Kill Isaac with Eden

YOU > Evil...Caves Conquer all Caves of Evil
with Kisuke and Momohime.

Endangered Lizards Killed all shining lizards

A New Blue Completed Ending Three

The Philanthropist Gave 50 presents.

Complicity Completed Ending Four

A Perfect 10 Earn a PERFECT medal on Zone 10.

Climber Reached top of the shrine

Two Birds Smack a bomb so that kills two or more enemies (Individual)

Halfway there Achieve half of your secondary goals.

Off with Its Head! Decapitated a medusa.

Good Father Collect all robot pieces

Ultimate Portal Knight Unlock all other trophies.

Peace Took refuge in an illusion.

The Veteran Defeated 3,000 enemies.

Xenophobe Kill a UFO!

Complete Chapter Four Completed Chapter Four

Devastator Deal 20 combat damage to a player in a single turn in a game

…for the future Look at Dana's drawing in the cement with Kate.

Harmonic Convergence Pick up all traveler instruments simultaneously with your signalscope.

At Least You'll Get A Trophy For It… Die while a Boss is Exploding

The final concert Leave the Musicians District

Insert Coin Complete all achievements in one game from The Arcade.

Choppy Chop Chop up 50 bodies

A Momentous Decision Awarded for making a difficult decision at the end of an already long and arduous quest.

Respect for the dead Plundered all four resting places

Ergophobia Earn every other trophy.

The Book Of Secrets Kill Satan with Eden

Unexpected encounter Leave Misty Bridge with Colonel Blake

The Final Fight Awarded for fulfilling your destiny at last.

Algorithmic Composition Algorithmic Composition

But Wait - There's More! On any Armored Transport heist, find the plans that unlocks the Train Heist.

Be prepared Fill the water bottle before leaving base camp.

Mighty Wander Max out stamina bar

The super resistant Find the poster of the super resistant.

Upsetting discovery Leave the cemetery.

The letter Retrieve Dana's letter from the automaton.

Grief accomplished Get on board for a new destination.

Brand Equity Complete any manufacturer challenge category.

Cyclops Abridged Crossed a cyclopean bridge.

Breach Enter the Breach.

Complete Chapter Five Completed Chapter Five

Lazarus' Rags Kill Isaac with Lazarus

Battle Brother Get a Multiplayer character to Lvl 10.

Insanity III Complete all three games in Mass Effect Legendary Edition on Insanity without changing difficulty

The Postman Delivered the journal to Lucien.

Police Brutality Beat a Shield to death using the Telescopic Baton.

The Laborer Completed 50 notice board quests.