MMDE

Tread Not So Softly Kill an enemy by jumping on top of them.

Feeling Lucky, Punk Detonate multiple Magnum rounds to kill 2+ enemies at once, 5 times

Chapter IV Kill the Crow Witch

Commander Of Magic Purchase all techniques.

Brawler Buy 15 combos

Annihilation Kill 100 aliens

Waste Not Get 5 headshot kills with one Deadeye clip

Tag, You're It Kill 40 Bullseye tagged enemies

Seasoned Acquire 20000 experience points

Double, Double, Toil And Trouble Create 20 Concoctions.

Chapter V Gain access to the Vampire Castle

Chapters 8-11 (Normal) Complete Chapters 8 through 11 on Normal difficulty.

Turd Burglar Find and steal a piece of poo

First Step Complete your first mission in Jimmy's Vendetta.

Wicked Weave Master Execute 20 Wicked Weave attacks while using Dodge Offset.

Raining Limbs Kill 25 Grims using only grenades

Vehicular Manslaughter Destroy 10 Warden vehicles while on the train

Chapters 12-13 (Normal) Complete Chapters 12 and 13 on Normal difficulty.

Chapter VI Leave the Refectory with the Butcher's key

Bloodborne Kill 3 enemies simultaneously using a single mutated body

Chapter VII Survive the encounter with Laura

Natural Disaster 3x Kill 3 aliens at once

Chapter VIII Acquire the power of the second Dark Lord

Umbra Witch Complete all Chapters on Normal difficulty.

BARF! Make 6 Wardens puke at the same time in the prison

Pit Champion Defeat the Battlelord in Las Vegas

What Witness? Finish the Witness level in "Joe's Adventures."

Chapters 14-Epilogue (Normal) Complete Chapters 14 through the Epilogue on Normal difficulty.

Chapter IX Persuade Baba Yaga to open a portal to the Necromancer area

Chapter X Vanquish the Gravedigger

Shoot the Messenger Defeat 3 Agitator Majini in one playthrough of "Desperate Escape."

Chapter XI Acquire the power of the third Dark Lord

Big Guns, Big Ships Blow up 5 enemy Gunships or Dropships

Skirmish Finish all levels in Esquire difficulty

Chapter XII Defeat Satan and save the world

DING! Running off will get you nowhere

Nuclear Devastation Kill 250 aliens

It's All About the Points Score at least 40,000 points in Survivors.

Overload Use the EMP to take down 10 Steelhead Auger shields

One Eyed Jack Find and kill 'Jack' in Graterford Prison

No Escape Destroy all Warden vehicles in the Motorpool

Frickin' Laser Beams Get to the first mineshaft without being hit by sniper fire in Mt. Pleasant, PA

Snipe Hunt Collect all Deadeye rifles without dying while fighting the Widowmaker in St. Louis

Medusa Freeze 5 enemies at once and destroy them with a blast of the Cryogun's secondary fire

In This Together Defeat the Widowmaker in Times Square without killing a single Hybrid

The Deepest Cut Kill 20 enemies using only Iai-Jutsu with Shuraba. (Iai-Jutsu performed by holding △ button.)

Keep the Good Times Rolling Chain a 20-defeated combo in Slayers.

Baron von Nukem Shoot down 20 alien fighters

Substance Abuser Drink beer while on steroids or vice-versa in SP

Not Bad for a Human Defeat the Alien Queen