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Four of a Kind Kill 4 enemies in a row with headshots in the single player campaign.

Completed Cohen's Masterpiece The player has completed Sander Cohen's great masterpiece

Save the Bacon Protect 'War Pig', the Abrams tank.

Shock Tactics Retrieved Shock Jockey.

Maxed One Track The player has purchased every slot in one of the Plasmid or Tonic tracks

Two Fully Upgraded Weapons The player has fully upgraded two weapons

Defeated Andrew Ryan The player has defeated Andrew Ryan

Daredevil Kill an enemy while blinded by a flashbang in the single player campaign.

Skilled Hacker The player has successfully completed 50 hacks

Broke Fontaine's Mind Control The player has broken Fontaine's mind control

Death From Above Operate an AC-130 gun ship.

Became a Big Daddy The player has become a Big Daddy

Defeated Atlas The player has defeated Atlas

Coins in the Cushion In the Main Campaign, looted 200 containers.

First Class Ticket In the Main Campaign, boarded The First Lady.

Rescue Roycewicz Save Pvt. Roycewicz on the stairs.

Straight Flush Kill 5 enemies with one shot while in the AC-130 gunship.

Three Fully Upgraded Weapons The player has fully upgraded three weapons

Death Mode: Purgatory #1 Complete the Death Mode level.

David & Goliath In the Main Campaign, killed 20 "Heavy Hitter" enemies.

Roadkill Kill 2 enemies by blowing up a car in the single player campaign.

Down Boy Down Survive a dog attack.

Wrong Number Find Al-Asad's safehouse.

Death Mode: Sneak n' Deke Complete the Death Mode level.

Explosion Man Kill 20 enemies with explosives in a single level.

Tear 'em a New One In the Main Campaign, opened 30 Tears.

Armed Revolt Assisted the gunsmith.

No Rest for the Weary Stab an injured crawling enemy.

Vigorous Opposition In the Main Campaign, killed 75 enemies either with a Vigor or while the enemy is under the effects of a Vigor.

Fully Researched Gun Splicer The player has fully researched the Leadhead Splicer

Death Mode: Rowdy Cloudy Complete the Death Mode level.

Death Mode: Purgatory #2 Complete the Death Mode level.

Should Auld Acquaintance... Unlocked 1999 Mode.

Working Class Hero In the Main Campaign, completed the Factory.

Ammo Inventor The player has successfully invented all possible ammo types

Reinforcement Denied Kill at least 3 rappelling enemies in a single rope.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

Piggyback Ride Carry Cpt. MacMillan to safety.

Blood in the Streets Completed Emporia.

Street Sweeper In the Main Campaign, killed 50 enemies with the Founder China Broom Shotgun or Vox Heater.

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

The Roguish Type In the Main Campaign, used Elizabeth to pick 30 locks.

Higher Learning Completed Comstock House.

Desperate Measures Corner Zakhaev's Son.

On a Clear Day... In the Main Campaign, killed 30 enemies with the Bird's Eye Sniper Rifle.

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Four Fully Upgraded Weapons Fully upgrade four weapons

Win the War Complete the game on any difficulty.

Tin Soldier Completed the Main Campaign on Easy difficulty or above.