Ephryx

Just Scratched the Surface Collect all Dead Drops in the Neon District.

Good Intentions Good guys work for the greater good.

Everything Lost Again Complete Act 01

250 Headshots Defeat 250 Enemies with Headshots

30 Kills: RPG-7 Kill 30 Enemies with the RPG-7

A Speedy Reunion Beat 'Chapter 16 - The Treasure Vault' in less than 7 minutes

Maxed Out! Completely upgrade all weapons

Charted! - Crushing Finish the Game on Crushing Without Changing the Difficulty

Proficient Fortune Hunter Find 60 Treasures

Micolash, Host of the Nightmare Defeat Micolash, Host of the Nightmare.

Ammo Inventor The player has successfully invented all possible ammo types

Cainhurst Gain entry to Cainhurst, the lost and ruined castle.

Eye Candy Collect all of the Gorgon Eyes

All Control Towers disabled Disabled all Control Towers by overriding or destroying them.

Chalice of Ailing Loran Acquire the Chalice of Ailing Loran that seals
the tragic land lost to the sands.

Amygdala Defeat Great One: Amygdala.

Horn of Plenty Collect all of the Minotaur Horns

Mergo's Wet Nurse Defeat Great One: Mergo's Wet Nurse.

Fully Researched Thug Splicer The player has fully researched the Thuggish Splicer

In Perseus's Image Defeat Medusa.

The Choir Gain entry to the realm of the Choir,
the high stratum of the Healing Church.

Civic Leader Take over all territory in the Warren.

Master of the Hunt Complete the Daughters of Artemis questline.

Maxed All Tracks Purchased every slot in all four Plasmid and Tonic tracks

Everybody Benefits Complete Markos's questline.

Urban Designer Take over all territory in the Historic District.

Member of the Mineral Club Find 50% of the Shards.

Expert Fortune Hunter Find 80 treasures

Martyr Logarius Defeat Martyr Logarius.

Doctor Cole Heal 250 pedestrians.

Celestial Emissary Defeat Great One: Celestial Emissary.

Men at Work Complete Chapter 14.

Upgraded Every Pouch Type Upgraded the Food Pouch, Potion Pouch, Resource Pouch, Trap Pouch, and any ammo pouch at least once.
1/5

Steel Fist Master Kill 20 Enemies with a Single Punch After Weakening Them with Gunfire

Fully Improved Weapons Acquired the improved versions of three weapons from Varga.

Proper Scrapper Sell five vehicles to Mike Bruski at the scrapyard.

Finish Him Finish What you started.

Little Sister Savior The player has completed the game without harvesting any Little Sisters

Fully Researched Spider Splicer The player has fully researched the Spider Splicer

Four Fully Upgraded Weapons Fully upgrade four weapons

Cosplay Kill an Enemy While Playing as an Alternate Character Costume Other Than Drake

Chalice of Isz Acquire the Great Chalice of Isz that seals
the home of the cosmic kin.

Ebrietas, Daughter of the Cosmos Defeat Great One: Ebrietas, Daughter of the Cosmos.

Master Fortune Hunter Find 100 Treasures

Island Hopper Complete 20 Quests on Pephka, Obsidian and Abantis islands.

Weapon Master Acquire a weapon of the highest level.

Master Thief Collection Find all Treasures and the Strange Relic

End of the Rainbow Settle the score with the Irish once and for all.

It’s getting hot in here... Burn 100 enemies with the Bow of Apollo

Trust Me, I'm a Doctor Complete the Hippokrates questline.