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Splashdown! Shoot down the hydroharvesters on Pokitaru.

Handy Man Upgrade a building in the Stronghold.

Macho Man Defend a woman's honor.

Tip of the Iceberg Use your Eagle Vision to scan a Glyph in the environment.

I like the view Synchronize 10 View Points.

Ferocious Oxide Defeat Victor in the Phoenix.

Undertaker Discover the Assassin's Tomb inside the catacombs under Santa Maria Novella.

High Dive Perform a Leap of Faith from the Top of Florence's Giotto's Campanile.

…Bada Boom! Defeat 20 Enemies in a row with Homing Missiles

Bloody Sunday Complete DNA Sequence 4.

Radical Win the hoverboard Bronze Cup on Kalebo.

A Piece of the Puzzle Unlock a piece of Subject 16's video.

Hero of the People Liberate 12 occupied areas in Izuhara.

Flash of Steel Defeat 20 enemies with a counterattack after a Perfect Parry.

A Change Of Heart Defeat Captain Qwark on the Deplanetizer.

Mailman Intercept a Borgia Courrier.

Let eM In Mike allowed Emily to stay in the basement

Scream Too! Mike cut off his fingers to free himself from the bear trap

The Conspirators Complete DNA Sequence 5.

An Unexpected Journey Complete DNA Sequence 6.

The End Of The Beginning Defeat Dr. Nefarious on the Deplanetizer.

Choir Boy Discover the Assassin's Tomb inside Santa Maria del Fiore (The Duomo).

Bleeding Effect Complete training and reenter the Animus.

Pool Sharks Are The Worst Get eaten by a Pool Shark in the Pokitaru Ocean.

A Charming Man Equip a charm in all 6 slots.

Man of the People Toss more than 300 florins on the ground.

Abby Normal Collect every Telepathopus brain.

Every Trick in the Book Acquire all the throwable Ghost Weapon techniques.

Assassin For Hire Complete your first assassination mission for Lorenzo Il Magnifico.

The Merchant of Venice Complete DNA Sequence 7.

Go Speed Ratchet, Go! Win the Gold Cup on both Rilgar and Kalebo.

Steal Home Win a race against thieves.

Street Cleaner Hide 5 dead bodies in a Bale of Hay.

The Impenetrable Palazzo Complete DNA Sequence 8.

I can see your house from here! Discover the Assassin's Tomb inside the Torre Grossa.

Professional Complete 50% of all Challenges

A Fight For The Isle…. Liberate all occupied areas in Izuhara.

Kleptomaniac Pickpocket 1000 Florins.

Good Riddance Liberate 8 occupied areas in Toyotama.

Private Eye Sleazy Place - Lead Lauren to talk about her son

Masquerade Complete DNA Sequence 9.

The Headstrong Thief Complete all of Yuna's Tales.

The Perfect Storm Fully upgrade your sword.

Bianca's Man Complete DNA Sequence 10.

Prison Escape Discover the Assassin's Tomb inside the Rocca di Ravaldino fortress.

Know Your Enemy Collect 20 Mongol artifacts.

The Prophet Complete DNA Sequence 11.

Monochrome Masters Purchase an item from the Black and White Dye Merchants.

The Skilful Wolf Man Mike kept the wolf alive throughout the Sanatorium

All in the Wrist Defeat the maximum amount of enemies within a single Standoff.