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Inefficient Medicine Reach an ending with the Ironman and Withered Health modifiers enabled.

Sester Unlock Sester Genessa

Guns. Lots of Guns Unlock all Sidearms
1/8

For Science! Defeat Angelo Agnus with an SSS ranking in Son of Sparda Mode or higher.

A Gruelling Journey Reach an ending with the Tremendous Vestige Decay and Ironman modifiers enabled.

Lord of Slaughter Reach an ending with the Ironman and Enemy Density modifiers enabled.

30,000,000 Points Get a score of 30,000,000 points or more!

This Channel Sucks Break all the Skullmageddon monitors in the Rocket Dojo

Lord of War Unlock all Weapons
1/8

Ascension Discover the secret of the Mango

Good for Your Eyes! Kill a bunny with a carrot.

Secrets Exposed Clear all secret missions as Nero, Dante, or V.
1/12

Terminated Kill the Robot's Past

MYSTERY DOOR FIND THE SECRET DOOR IN VODKAVILLE

Dungeon Master Reach Overall Player Level 20.

First Flag on the Chopper Complete Contra (JP)

Destined to be Extreme Refine all Destiny Talismans to level 7. (Excludes DLC.)

Retro Rampage Beat All Warpzones

Totally Texas Reach Player Level 50.

The City is Slicker Complete Mission 2.

Play Another Day Reverse time by a day.

The Sky is the Limit Perform an aerial combo.

Shell Seeker Unlock all Shells
1/8

Transcendence Use the Stigma of Transcendence.

Architect of Knowledge Deliver all of the blueprints to Mariano.

Gnawing hunger sets in... Lose a hero to hunger

Edison In a single game, complete every Research Project.

Rearm and Repeat Collect more than 100 Devil Breakers during missions. (Nero only)
61/100

Master Smith Upgrade any primary weapon to its maximum level.

Still Sharp After One Year Complete Super C

Out of Line Complete the Shores of the Dead on Normal difficulty.

Don't Make Me Slap You! Slap 20 objects out of enemy's hands in online games

King Pushy Win an Arena chapter by using push only.

Praise him! Defeat The Monolith

Ultimate Gainz Defeat Malborn Offspring

Apothecary Acquire all Healing Holsters.

Child’s Play Finish Madelyne and Theodora's quest.

Salt Boy Beat The Salt Factory light world without dying

Ice Creamed Reach the Temple.

The Fruits of Ambition Draw the curtain on Sergei's ambition.

Zombie Killer Reach the zombie wave in each Survival map

To The Rooftops Completed all Area 2 levels on any difficulty setting

Beat up the Bully Defeat The Little Giant again.

Lost Your Head Defeat Orrem, the Reclaimed

Insomnia Defeat the Harbinger of Nightmare.

Not Another Zombie Game Win a game with the Necroa Virus without making a single zombie

Nice to Beak You Have Beaknose defeat 10 enemies

Serial Quester Complete Quests of 5 different rarity levels.

Just a Scratch Defeat Albotenstein with 75% health or more

Fully Loaded Acquire all Federal Era Belts.